Verified BPS-Pharmacotherapy exam dumps Q&As with Correct 175 Questions and Answers
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NEW QUESTION 63
A pharmacotherapy specialist is conducting a pharmacokinetic study of a drug. The pharmacokinetic profile of this drug is best described by a one-compartment model with a mean elimination rate constant of 0.173/h. The standard curve for the assay to be used covers the range of 5-40mcg/mL. Samples are collected shortly after single intravenous bolus drug administration, and at 4 and 8 hours after dosing. Preliminary analysis shows that the 4-hour sample concentration is 25 mcg/mL. In this situation, which of the following statements is correct?
- A. Both the initial and 8-hour concentration points are probably outside the range of the standard curve and cannot be reliably measured without diluting the samples.
- B. The initial plasma concentration is probably outside the range of the standard curve' it may be possible to dilute the sample and re-assay.
- C. All plasma concentrations are probably within the range of the standard curve and can be reliably measured.
- D. Both the initial and 8-hour concentration points are probably outside the range of the standard curve but can be reliably quantitated by extrapolating the curve to higher and lower points.
Answer: C
NEW QUESTION 64
A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?
- A. Report the event to the FDA MedWatch program.
- B. Complete a manufacturer's adverse event report.
- C. Write and submit a case report detailing the event.
- D. Report the event to the P & T Committee.
Answer: C
NEW QUESTION 65
A patient with diabetic ketoacidosis is receiving 0.9% NaCl, with potassium chloride 20 mEq/L, at 200 mL/h, and regular insulin 8 units/h, intravenously. After 8 hours, the blood glucose is
250 mg/dL and the anion gap is elevated. At this point, which of the following is the most appropriate therapy?
- A. Convert to subcutaneous regular insulin and reduce fluids to a keep-vein-open rate.
- B. Discontinue the insulin and maintain current fluids.
- C. Continue the insulin infusion rate and change to dextrose-containing fluids.
- D. Continue the current insulin and fluid therapy.
Answer: D
NEW QUESTION 66
A patient is admitted to the hospital after a motor vehicle collision. The patient takes methadone
40 mg once daily for management of an opiate addiction. The remainder of the patient's medical history is unremarkable. The medical resident caring for the patient wants to order methadone but Expresses concern related to the Substance Abuse and Mental Health Services Administration (SAMHSA) regulations.
What is the appropriate action?
- A. Order morphine at equivalent dose as an alternative management.
- B. Order methadone 40 mg once daily if the medical resident is a registered opioid treatment program (OTP) practitioner.
- C. Order methadone 40 mg once daily during inpatient treatment.
- D. Order methadone 40 mg once daily if the patient shows signs of withdrawal.
Answer: C
NEW QUESTION 67
A 48 year old man attends a local pharmacy health fair for a blood pressure check. His blodd pressure on two recent occasions has averaged 138/88 mm Hg.
According to the American Society of Hypertension, what is this patient's blood pressure classification?
- A. Prehypertension
- B. Stage 1
- C. Stage 2
- D. Normotensive
Answer: A
NEW QUESTION 68
A 58-year-old man recently diagnosed with chronic stable angina has discontinued metoprolol due to erectile dysfunction. Medical history also includes hypertension and type 2 diabetes mellitus. The patient's current medications include aspirin, lisinopril, metformin, and sublingual nitroglycerin as needed. BP is 128/76 mm Hg, and HR 88 bpm.
Which of the following is the most appropriate choice to manage the patient's stable angina symptoms?
- A. Atenolol
- B. Diltiazem CD
- C. Vardenafil
- D. Amlodipine
Answer: B
NEW QUESTION 69
A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?
- A. 0
- B. 1
- C. 2
- D. 3
Answer: A
NEW QUESTION 70
A patient presents with palpitations and shortness of breath. A 12-lead ECG reveals a regular narrow QRS complex supraventricular tachycardia. What is the recommended first-line therapy?
- A. Amiodarone
- B. Verapamil
- C. Adenosine
- D. Lidocaine
Answer: C
NEW QUESTION 71
A patient with recently diagnosed Iymphoma is receiving doxorubicin, bleomycin, vinblastine, and dacarbazine. Aggressive intravenous hydration is required to decrease the complications associated with which of the following?
- A. Tumor lysis syndrome
- B. Doxorubicin cardiomyopathy
- C. Dacarbazine nephrotoxicity
- D. Bleomycin pulmonary toxicity
Answer: A
NEW QUESTION 72
An obtunded 61-year-old Woman weighing 45 kg with Worsening renal function is admitted to the hospital. She has a recent history of several days of nausea, fatigue, pruritus, and a metallic taste in her mouth. Her medical history includes diabetes, heart failure, and COPD. Admission laboratory values include:
SERUM CHEMISTRY
Sodium: 135 mEq/L
Potassium: 5.7 mEq/L
Chloride: 100 mEq/L
HCO3: 15 mEq/L
BUN: 96 mg/dL
Creatinine: 5.5 mg/dL
Glucose: 300 mg/dL
Calcium: 7.4 mg/dL
Serum ketones: Negative
ABGS (Room Air)
pH: 72
PaCO2: 30 mm Hg
PaO2: 75 mm Hg
O2 Sat: 90%
Chest X-ray shows a flattened diaphragm. Current medications include furosemide, fluticasone salmeterol, and glipizide. Which acid-base disorder does this patient exhibit?
- A. Metabolic acidosis secondary to end-stage renal disease
- B. Metabolic acidosis secondary to diabetic ketoacidosis
- C. Respiratory acidosis secondary to COPD
- D. Metabolic acidosis secondary to furosemide use
Answer: A
NEW QUESTION 73
A 53-year-old man has been diagnosed with a deep vein thrombosis. Weight = 94kg and height
= 170 cm. Creatinine clearance F 60 mL/min, CBC results are within normal limits, and baseline INR = 0.9.
The pharmacotherapy specialist receives orders for warfarin 5 mg orally every evening and enoxaparin 80 mg subcutaneously every 12 hours. Which of the following is the best course of treatment?
- A. Continue enoxaparin 80 mg every 12 hours.
- B. Change enoxaparin to 140 mg every 24 hours.
- C. Change enoxaparin to 80 mg every 24 hours.
- D. Change enoxaparin to 100 mg every 24 hours.
Answer: C
NEW QUESTION 74
A 59-year-old man presents to the neurology clinic with recently diagnosed Parkinson's disease.
At his last visit 2 months ago, selegiline therapy was instituted, and he is tolerating it well. The patient still complains of tremor and rigidity that are interfering with both professional and leisure activities. Which option is most appropriate at this time?
- A. Change to carbidopa/levodopa.
- B. Change to ropinirole.
- C. Change to amantadine.
- D. Change to entacapone.
Answer: A
NEW QUESTION 75
A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?
- A. Change glipizide to insulin.
- B. Continue with glipizide and add metformin.
- C. Change glipizide to metformin.
- D. Increase glipizide to 20 mg twice daily.
Answer: C
NEW QUESTION 76
A 59-year-old patient who is HIV-positive is receiving darunavir and ritonavir as part of a highly active antiretroviral therapy program. Which herbal supplement is contraindicated for this patient because it would decrease darunavir concentrations?
- A. Echinacea
- B. Kava kava
- C. St. John's wort
- D. Saw palmetto
Answer: C
NEW QUESTION 77
An investigator decides to perform a correlation analysis of the relationship between the number of cigarettes smoked per day and age. Results show a positive correlation between the two, with an r value of 0.50 and ap value for the correlation equal to 0.03. What is the most reasonable interpretation of this correlation?
- A. Increased age does not cause students to smoke more.
- B. There is no relationship between age and amount of smoking.
- C. There is a statistically significant numerical association between age and amount of smoking.
- D. Increased age causes students to Smoke more.
Answer: C
NEW QUESTION 78
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